Inflammation is coming clearly into focus as a primary driver of noncommunicable disease. Repeated stimulation or persistence of the inflammatory response lead to dysfunction. Chronic inflammation may manifest in nearly any area of the body and is at the root of many diseases of aging.
Heart disease is the number one killer in the U.S. It is also a major cause of disability. There are many different forms of heart disease. The most common cause of heart disease is narrowing or blockage of the coronary arteries, the blood vessels that supply blood to the heart itself. This is called coronary artery disease and happens slowly over time.
As one of the cell’s most critical components, these organelles are also one of the most susceptible to dysfunction. Progressive toxicity—from pharmaceuticals, the environment, pesticides, and even byproducts of their own metabolism—results in fewer mitochondria and a corresponding loss of energy.